A Comparison of Weekly DCF versus Standard DCF as First-line Systemic Chemotherapy for Metastatic Gastric Cancer Patients
نویسندگان
چکیده
منابع مشابه
One-day DCF regimen in patients with metastatic gastric cancer.
BACKGROUND Cytotoxic chemotherapy is the basic treatment for metastatic gastric cancer. The "docetaxel, cisplatin, 5-day infusion of 5-FU (DCF5)" regimen is regarded as an effective therapy. However, the poor toxicity profile of this regimen and administration by 5-day infusion are major drawbacks of this method. METHODS Patients with measurable metastatic gastric carcinoma, Eastern Cooperati...
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Objective: In this study, we investigated the correlation between the degree and timing of chemotherapyinduced neutropenia (CIN) caused by the DCF (docetaxel-platinum-fluorouracil) regimen as first-line chemotherapy and the survival of patients with advanced gastric cancer. Methods: We retrospectively analysed 110 patients diagnosed with advanced gastric cancer between 2007 and 2012 at our hosp...
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Docetaxel and cisplatin plus fluorouracil (DCF) is one standard regimen in the treatment of advanced gastric cancer (AGC). Due to substantial toxicity of DCF, modified DCF regimens have been developed to improve efficacy and safety. This study aimed to compare the clinical efficacy and safety between the standard DCF regimen and three common modified DCF regimens. A total of 97 consecutive AGC ...
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Abstract Introduction: Gastric cancer is the fourth common cancer and the second leading cause of cancer death worldwide. Due to lack of adequate information on the side effects of chemotherapy regimens in treatment of gastric cancer, this study was aimed to determine the side effects of two common chemotherapy regimens of gastric cancer. Methods: This prospective study was conducte...
متن کاملComparison of the incidence and severity of side effects profile of FOLFOX and DCF regimens in gastric cancer patients
Abstract Introduction: Gastric cancer is the fourth common cancer and the second leading cause of cancer death worldwide. Due to lack of adequate information on the side effects of chemotherapy regimens in treatment of gastric cancer, this study was aimed to determine the side effects of two common chemotherapy regimens of gastric cancer. Methods: This prospective study was conducte...
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ژورنال
عنوان ژورنال: West Indian Medical Journal
سال: 2017
ISSN: 0043-3144
DOI: 10.7727/wimj.2016.536